草榴社区

基于自由基反应开发新型有机合成方法构建胺类化合物及其在药物活性分子中应用

1.Jian Wang. Transition-metal-free, visible-light-induced multicomponent synthesis of allylic amines and tetrahydroquinolines. Org. Chem. Front. 2022, 9(13): 3452-3459.
2.Jian Wang, Jiang-Hua Li, Yidong Guo, Hongbo Dong, Qiang Liu, and Xiao-Qi Yu. TEMPO-Mediated C–H Amination of Benzoxazoles with N-Heterocycles. J. Org. Chem. 2020, 85(19): 12797-12803.
3.Jian Wang, Xingdong Xu, Hoa Phan, Tun Seng Herng, Tullimilli Y. Gopalakrishna, Guangwu Li, Jun Ding, and Jishan Wu* Stable Oxindolyl-Based Analogues of Chichibabin’s and Müller’s Hydrocarbons. Angew. Chem. Int. Ed., 2017, 56, 14154 -14158.
4.Jian Wang, Gakhyun Kim, María Eugenia Sandoval-Salin, Hoa Phan, Tullimilli Y. Gopalakrishna,Xuefeng Lu, David Casanova,* Dongho Kim,* and Jishan Wu. Stable 2D anti-ferromagnetically coupled fluorenyl radical dendrons Chem. Sci., 2018,9, 3395-3400.
5.Jian Wang, Shan Wang, Gao Wang, Ji Zhang* and Xiao-Qi Yu*. Iron-mediated direct arylation with arylboronic acids through an arylradical transfer pathway. Chem. Commun. 2012, 48, 11769–11771.
6.Jian Wang, Ji-Ting Hou, Jun Wen, Ji Zhang* and Xiao-Qi Yu*. Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air. Chem. Commun. 2011, 47, 3652–3654.

纵向项目：
低毒性对苯二腈作氰源的自由基氰基化反应研究
横向项目：
氮杂卡宾类有机小分子的合成与开发