草榴社区

不对称催化；有机合成方法学

1. You, Y.; Gan, G.-Y.; Duan, S.-Y. Zhang, Y.-P.; * Li, Q.; Wang, Z.-H.; Zhao, J.-Q.; Liu, X.-L.; Yuan, W.-C. * Enantioselective [3 + 2] annulation of tryptanthrin- derived ketimines and 2-naphthols: access to polycyclic indolo[2,1-b]quinazoline derivatives. Org. Chem. Front. 2024, 11, 2002.
2. Zhuo, J.-R.; Zhao, J.-Q.; * Yang, L.; Wu ,Y.-L.; Zhang, Y.-P.; You, Y.; Wang, Z.-H.; Zhou, M.-Q.; Yuan, W.-C.* Thiol-Triggered Tandem Dearomative Michael Addition/ Intramolecular Henry Reaction of 2-Nitrobenzofurans: Access to Sulfur-Containing Polyheterocyclic Compounds. Org. Lett. 2024, 26, 2623.
3. Zhang, Y.-P.; You Y.; Yin, J.-Q.; Wang, Z.-H.; Zhao, J.-Q.; Yuan W.-C. Progress in Catalytic Asymmetric Reactions with 7-Azaindoline as the Directing Group. Molecules 2023, 28, 7898.
4. Zhang, Y.-P.; You Y.; Yin, J.-Q.; Wang, Z.-H.; Zhao, J.-Q.; Li Q.; Yuan W.-C. Asymmetric Propargylic C-C Bond Formation Using Metal–Allenylidene Species. Eur. J. Org. Chem. 2023, e202300728.
5. You, Y.; Gan, G.-Y.; Duan, S.-Y. Zhang, Y.-P.; Li, Q.; Wang, Z.-H.; Zhao, J.-Q.; Liu, X.-L.; Yuan, W.-C. Enantioselective synthesis of tryptanthrin derivatives enabled by an asymmetric aza-Friedel–Crafts reaction. Org. Chem. Front. 2023, 10, 5421.
6. You, Y.; Zhang, Y.-P.; Wang, Z.-H.; Zhao, J.-Q.; Yin, J.-Q.; and Yuan, W.-C. Recent advances in copper-catalyzed decarboxylative reactions of propargylic cyclic carbonates/carbamates. Chem. Commun. 2023, 59, 7483-7505.
7. Ting Wang, Yong You, Zhen-Hua Wang, Jian-Qiang Zhao, Yan-Ping Zhang, Jun-Qing Yin, Ming-Qiang Zhou, Bao-Dong Cui*, and Wei-Cheng Yuan. Copper-Catalyzed Diastereo- and Enantioselective Decarboxylative [3 + 2] Cyclization of Alkyne-Substituted Cyclic Carbamates with Azlactones: Access to γ-Butyrolactams Bearing Two Vicinal Tetrasubstituted Carbon Stereocenters. Org. Lett. 2023, 25, 8, 1274-1279.
8. You, Yong, Li, Ting Ting, Sun, Ting Jia, Zhang, Yan Ping, Wang, Zhen Hua, Zhao, Jian Qiang, Yuan, Wei Cheng. Enantioselective Construction of Vicinal Quaternary-Tetrasubstituted Carbon Stereocenters by Copper-Catalyzed Decarboxylative Propargylic Substitution. Org. Lett. 2022, 24(41), 7671-7676.
9. Wang, Zhen Hua, Liu, Ji Hong, Zhang, Yan Ping, Zhao, Jian Qiang, You, Yong, Zhou, Ming Qiang, Yuan, Wei Cheng. Cu-Catalyzed Asymmetric 1, 3-Dipolar Cycloaddition of N-2, 2, 2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of N-Arylmaleimides: Access to Enantioenriched F3C-Containing Octahydropyrrolo [3, 4-c] pyrroles. Org. Lett. 2022, 24(22), 4052–4057.
10. Shen, Li Wen, Zhang, Yan Ping, You, Yong, Zhao, Jian Qiang, Wang, Zhen Hua, Yuan, Wei Cheng. Inverse Electron-Demand Aza-Diels–Alder Reaction of α, β-Unsaturated Thioesters with In Situ-Generated 1, 2-Diaza-1, 3-dienes for the Synthesis of 1, 3, 4-Thiadiazines. J. Org. Chem., 2022, 87(6), 4232-4240.

授权专利：
1. 炔丙基取代的手性3-氨基-3,3-双取代氧化吲哚类化合物、其合成方法及应用。2024，CN115215783 B [P]。
2. 手性3-螺环氧化吲哚并苯并噻吩砜类衍生物、其制备方法及用途。CN202310215209.9[P]。
纵向项目：
1. 主持草榴社区 人才项目，2022-02至2027-02。
2. 参与国家自然科学基金面上项目22171151, 2022-01-01 至 2025-12-31。