草榴社区

药物合成、抗肿瘤新药研究、生物医用新材料研究。

1.Yiwen Zeng, Yue Zeng, Xudong Zhu, Lianmei Chen*, Xiaoqiang Guo*, Tairan Kang*, Synthesis of novel chalcone/lipoic acid derivatives and cross-linked chitosan for preparation of multi-functional packaging film, International Journal of Biological Macromolecules, 2025, 295, 138983.
2.Xudong Zhu, Pingge Yang, Yiwen Zeng, Lianmei Chen*, Xiaoqiang Guo*, Tairan Kang*, An antimicrobial packaging film based on a copolymer of lipoic acid-quaternary ammonium salt derivative and chitosan for its utilization in the preservation of grapes, Food Research International, 2025, 220, 117162.
3.Hong Liang, Xue-Xue Yang, Lian-Mei Chen*, Xing-Yu Chen, Xiao-Qiang Guo*, Tai-Ran Kang*, Stereoselective Synthesis of (Z)-β-Thioenamide from (Z)-Enamide-Iodines and Thiols under Mild Conditions, Eur. J. Org. Chem., 2024, e202400883.
4.Qing-Peng Liu, Lian-Mei Chen*, Chuang Zhou, Xiao-Qiang Guo*, Tai-Ran Kang*, Direct Aldimine Oxidative Reaction: A General Approach toward Amides, Asian J. Org. Chem., 2023, e202200615.
5.Lian-Mei Chen, Chuang Zhou*, Jing Li, Jun Li, Xiao-Qiang Guo*, Tai-Ran Kang*, Copper-catalyzed reactions of α,β-unsaturated N-tosylhydrazones with diaryliodonium salts to construct N-arylpyrazoles and diaryl sulfones, Org. Biomol. Chem., 2022, 20, 7011–7016.
6.Jun Li, Chuang Zhou*,Hong Liang, Xiao-Qiang Guo*,Lian-Mei Chen, Tai-Ran Kang*, Direct One-Pot Construction of Diaryl Thioethers and 1,3-Diynes through a Copper(I)-Catalyzed Reaction of λ³-Iodanes with Thiophenols, Eur. J. Org. Chem., 2022, e20220061.
7.Xu Sun, Xiao-Qiang Guo, Lian-Mei Chen*, Tai-Ran Kang*, Synthesis, Characterization of Spirocyclic λ³-Iodanes and Their Application to Prepare 4,1-Benzoxazepine-2,5-diones and 1,3-Diynes, Chem. Eur. J., 2021, 27, 4312–4316.
8.Xiaofei Du, Haiyan Jiang, Xiaoqiang Guo, Lianmei Chen*, Tairan Kang*, Synthesis of ferrocene/chitosan-AgNPs films and application in plasmonic color-switching and antimicrobial materials, Reactive and Functional Polymers, 2021, 169, 105061.
9.An-Jie Xia, Tai-Ran Kang*, Long He*, Lian-Mei Chen, Wen-Ting Li, Jin-Liang Yang, Quan-Zhong Liu*, Metal-Free Ring Expansion Reaction of Six-membered Sulfonylimines with Diazomethanes Generated in Situ from N-Tosylhydrazones: A New Approach toward Seven-membered Enesulfonamides, Angew. Chem. Int. Ed., 2016, 55, 1441-1444.

纵向项目:
1.国家自然科学基金面上项目(21672172)，2017.01-2020.12，主持；
2.四川省青年科技创新研究团队项目（2017TD0008）,2017.03-2020.03，团队带头人，主持；
3.中国博士后科学基金面上项目（2012M511933），2013.01-2014.12，主持；
4.四川省科技厅应用基础研究项目（2013JY0095），2013.01-2015.12，主持；
5.四川省教育厅重大培育项目（15CZ0016），2015.01-2017.12，主持；
6.科技部国家新药创制重大专项（2012ZX09103-301-030），2012.01- 2015.12，副组长。
横向项目:
1.横向项目：“新型核苷酸药物研发中化学中间体制备的关键技术研究”（2202080），2022.03-2027.03，主持。
2.横向项目：“肿瘤靶向治疗候选药物曲妥珠单抗 - 美登素偶联物的研发”，2012.01-2014.12，副组长。 3.横向项目：“高分子生物医用材料的合成及生物医用产品（封闭膜）的研发”（XTCX2014003），2014.01-2018.12，主持。
授权专利:
1.吲哚基甲酰胺类化合物及其制备方法，2021，中国专利 ZL 2018 1 0034100.4。
2.多取代的 1,2,4 - 三唑烷衍生物及其制备方法与应用，2017，中国专利 ZL 2014 1 0351765.X。
主编出版专著:
1.《综合化学实验》，主编，中国轻工业出版社，时间，2025年10月。