草榴社区

1.植物重要活性天然产物的生物合成规律及调控研究
2.活性天然产物靶标鉴定和作用机制研究

1.Daihan Chen, Min Sun, Yixi Yang, Benyi Tan, Dongsheng Ren, Yang Tao, Rui Li, Qi Zhao*. Comprehensive genome-wide analysis and functional characterization of the DIR gene family in Herpetospermum pedunculosum: insights from HpDIR16 and HpDIR17. Plant Physiology and Biochemistry, 2025,226,110074
2.Yu Xiao, Tianfeng Luo, Changsong Duan, Xinhui Wang, Yixi Yang, Rui Li, Jinpeng Deng, Qi Zhao*. Ethyl acetate extract from Herpetospermun cardigerum wall. Ameliorated concanavalin A-induced autoimmune hepatitis in mice by reprofiling gut microenvironment to modulate IDO1/KYN and PI3K/AKT/NF-κB pathways. Journal of Ethnopharmacology, 2025,345,9:119578
3.Yu Wang, Meihao Peng, Xin Yang, Liming Tu, Jiamin Liu, Yixi Yang, Rui Li, Xue Tang, Yuqing Hu, Guowu Zhang, Qi Zhao*, Qiuxia Lu*. Total alkaloids in Fritillaria cirrhosa D. Don alleviate OVA-induced allergic asthma by inhibiting M2 macrophage polarization. Journal of Ethnopharmacology, 2025,337:118935
4.Ziwei Zhu, Daihan Chen, Min Sun, Maotao Xiao, Peng Huang, Dongsheng Ren, Yixi Yang, Zhen Zhang, Qi Zhao*, Rui Li*. Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae). BMC Genomics,2024, 25:421
5.Meihao Peng, Jintao Li, Jie Zhou, Bowen Zhang, Jiaqing Liao, Di Yang, Yu Wang, Yixi Yang, Rui Li, Xue Tang, Qiuxia Lu*, Qi Zhao*. Total alkaloids of Fritillaria unibracteata var. wabuensis bulbus ameliorate chronic asthma via the TRPV1/Ca2+/NFAT pathway. Phytomedicine, 2023, 118: 154946
6.Ya Zhong, Bowen Zhang, Jintao Li, Xin Zeng, Junxia Pei, Yamei Zhang, Yixi Yang, Fulun Li, Yu Deng*, Qi Zhao*. Ethanol extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degradation of keratinocyte-derived ICAM-1 and CXCL9. Journal of Integrative Medicine, 2023, 21, 6: 584-592
7.Qiuxia Lu, Rui Li, Jiaqing Liao, Yuqin Hu, Yundong Gao, Mingcheng Wang, Jian Li*, Qi Zhao*. Integrative analysis of the steroidal alkaloids distribution and biosynthesis of bulbs Fritillaria Cirrhosae through metabolome and transcriptome analyses. BMC genomics, 2022, 23(1): 511
8.Yixi Yang, Yujin Zhang, Xun Chen, Zhou Su, Yu Deng, Qi Zhao*. Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL17A and IL-33 in keratinocytes. Journal of Ethnopharmacology, 2022, 292: 115124
9.Rui Li, Yang Zhang, Yucheng Wang, Kejia Huang, Qianye Yang, Tiantian Zhang, Kun Xie, Jian Li*, Qi Zhao*, Aqueous extract of Fritillariae cirrhosae induces cellular apoptosis through activation of STATs-mediated immunomodulation, Journal of Ethnopharmacology, 2020, 261
10.Jian Li, Wenwen Li, Kejia Huang, Yang Zhang, Gary Kupfer, Qi Zhao*. Chimeric Antigen Receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward. Journal of Hematology & Oncology. 2018,11 (1), 22

纵向项目：
1.国家自然科学基金面上项目，32570437，2026.01-2029.12，50万元，在研，主持
2.国家自然科学基金面上项目，32270407，2023.01-2026.12，54万元，在研，主持
3.国家自然科学基金青年项目，31600261，2017.01-2019.12，20万元，已结题，主持
4.四川省杰出青年科技人才项目，2022JDJQ0053，2022.01-2024.12，20万元，在研，主持
5.四川省省科技厅应用基础项目，2018JY0296，2018.01-2020.12，10万元，已结题，主持
6.四川省科技厅科技支撑项目，2013RZ0017，2013.10-2014.09，10万元，已结题，主持
7.四川省科技厅应用基础项目，2013JY0057，2013.01-2015.12，10万元，已结题，主持
8.成都市产业升级牵引工程-农业技术研发项目，2015-NY02-00366-NC，2017.06-2019.05，20万元，已结题，主持